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The Chicago Cubs (37-43) face off against the San Francisco Giants (38-42) on Wednesday for the third game of their four-game series. The game is set to start at 9:45 p.m. ET at Oracle Park. Let’s examine BetMGM Sportsbook’s lines for Cubs vs. Giants odds and provide expert MLB picks and predictions for the best bets.

Season series: Giants lead 3-2

Chicago has been outscored 10-5 in the first two games of this series, and the Cubs have lost three consecutive games overall. Since May 13, the Cubs have struggled on the road, posting a 4-14 record.

San Francisco entered this series on a five-game losing streak but is now seeking its third straight win, which would be its first since June 5-8.

Cubs at Giants projected starters:
– **RHP Hayden Wesneski** vs. **RHP Hayden Birdsong**

**Wesneski** (2-4, 3.29 ERA) is making his fourth start and 21st appearance. He has a 1.20 WHIP, 3.3 BB/9, and 8.1 K/9 over 41 innings pitched.
– Last outing: No-decision, 2 relief innings, 1 earned run, 2 hits, 2 walks, 2 strikeouts in an 11-1 home loss to the New York Mets on Friday.
– 2024 vs. Giants: 0-0, 18.00 ERA (1 IP, 2 ER), 1 H, 4 BB, 1 K in one relief appearance during a 7-6 home loss on June 17.
– Career vs. Giants: 0-2, 11.88 ERA (8 1/3 IP, 11 ER), 10 H, 7 BB, 8 K in one start and three relief appearances.

**Birdsong** is a 22-year-old making his MLB debut.
– Recently promoted from Triple-A Sacramento after just two weeks there.
– 2024 stats with Triple-A Sacramento: 1-0, 5.00 ERA (9 IP, 5 ER), 1.56 WHIP, 14.0 K/9 in two starts.
– Holds a combined 2.51 ERA across 57 1/3 innings at Double- and Triple-A.
– Considered one of the Giants’ top pitching prospects.

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